Role Globularia in the inhibition of calcium oxalate crystallization in vitro study

Plant extracts are known to modulate calcium oxalate (CaOx) crystallization. One of these is Globularia, the root and flower. Medicinals plants has been demonstrated be an efficient inhibitor CaOx crystal growth; however, its inhibitory activity against other events in crystallization not fully investigated. To assess potential Globularia as effective inhibitor, effects on nucleation aggregation were evaluated. Nucleation crystals studied by artificial urine prepared mixing stirring two equal volumes 50 ml solutions A B at constant temperature (37°C). In assay, was induced chloride sodium oxalate, The addition flower , acts phase growth crystallisation ; rate inhibition capacity concentration 100 % 96.09% 96.77% for 75% respectively, On note that inhibitors developed important low concentration. aggregation. Its presence kidneys may protect subjects kidney stone formation.